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The Essential Role of Effective Debridement in Supporting Wound Closure

Speaker: John C. Lantis II, MD

It has long been established that effective debridement plays an integral role in ensuring closure of chronic wounds. Whether this is frequent sharp debridement in combination with adjunctive therapies or before cellular and/or tissue-based therapy application, or whether it is permissive maintenance debridement allowing for the wound to close while still effectively removing the wound debris, every chronic wound requires some form of debridement.



Early Intervention in Chronic Wound Care

Wound Chronicity affects approximately 6.5 million Americans each year. Factors that delay healing, such as wound history and the presence of devitalized tissue, should be corrected in order to promote wound healing.


Quick Facts – Debridement and Chronic Wounds

Chronic and complex wounds are stalled in the inflammatory or proliferative phase of healing. These hard-to-heal wounds affect millions of people worldwide and impose a heavy financial burden on patients and health care systems. The goals of treatment in these patients are wound healing and limb salvage.


What Tissue Should You Remove From the Wound?

Tissue viability is crucial in managing all types of wounds, including surgical wounds, traumatic wounds, pressure injuries, lower-extremity ulcers, and skin tears. Accurate assessment and wound diagnosis are important…

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Enzymatic Debridement: How Does it Work?

Complex and hard-to-heal chronic wounds impact millions of people globally. In the United States, care for these types of wounds exceeds $25 billion annually. Wound healing naturally progresses through…

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Early Interventions for Limb Salvage

Approximately 2 million people in the United States are living with limb loss, and this figure is expected to double by 2050. Lower-limb amputation accounts for the vast majority of all amputations…

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What to Do When Sharp Debridement is Contraindicated

Sharp debridement is by far the fastest way to remove non-viable tissue from a wound bed. This modality must be performed by a licensed skilled practitioner using sharp instruments or tools to…

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How Much Do You Know About Debridement and Chronic Wounds?

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Debridement and Wound Care: Important Terms to Know

Collagenase: An enzymes that breaks the peptide bonds in collagen. Collagenases aid in destroying extracellular structures. Collagenase is one of the most frequently used enzymatic debridement agents.

Enzymatic debridement: A topical treatment that uses naturally occurring proteolytic enzymes or proteinases, which break down and remove devitalized tissue by digesting and dissolving this tissue in the wound bed.

Keratotic tissue: Keratotic tissue is the development of horny growths (keratomas). These growths can appear at the edges of wounds and hinder healing. They are removed by debridement to promote healing.

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