new practice accelerator logo small

Sponsored by

ON-DEMAND WEBINAR

The Effects of Biofilm and Prolonged Inflammation on the Wound Bed

Speaker: Gregory S. Schultz, PhD

Optimizing treatments to rapidly heal individual chronic wounds requires assessing multiple factors and implementing effective treatments to correct the problems that impair healing as described in the TIMERS guidelines, which emphasizes reducing the wound biofilm bioburden.

728x90_static

DOWNLOADABLE WHITE PAPER

How Biofilm and Prolonged Inflammation Affect the Wound Bed

Maintaining optimal wound bed conditions requires inflammation control and infection prevention. This includes preventing the formation of biofilms, which can delay healing. If biofilm prevention is not possible, wound care providers must optimize wound bed conditions to break the cycle of continuous inflammation and promote healing.

This white paper begins with the TIMERS (tissue, inflammation, moisture, edge, repair or regeneration, and social factors) framework for wound bed preparation. It then describes the roles of biofilm in delayed wound healing and persistent inflammation and concludes with specific strategies for biofilm prevention and reduction.

DOWNLOADABLE FACT SHEET

Quick Facts – Biofilm and Inflammation

Evidence shows that wound bed preparation is a critical step to promote healing. Cleansing, debridement, and the use of antimicrobial agents and dressings all aid in disrupting the biofilm and keeping an acute wound from becoming chronic.

This fact sheet contains essential information for wound care professionals on wound healing, biofilm formation and management, and the TIMERS framework for wound bed preparation.

READ THIS MONTH’S FEATURED ARTICLES

How Inflammation Affects Wound Healing

An injury to the human body initiates a wound healing chain reaction that occurs in four sequential but overlapping phases: hemostasis, inflammatory, proliferative and maturation. This post focuses on the…

Read More

What Are MMPs?

As scientists and researchers have delved deeper into the causes of wounds and wound chronicity, matrix metalloproteinases, or MMPs, have come into sharper focus. MMPs are not just present in chronic wounds — they also…

Read More

What Is the Wound Telling You?

Wound healing can stall for a number of reasons. Wounds that have not healed or significantly reduced in size after four to six weeks are considered chronic. They are characterized by a multitude of impeding factors including biofilm, excess matrix…

Read More

Inflammation and Pain

Wounds typically heal in four sequential but overlapping phases — hemostasis, inflammatory, proliferative and remodeling — ultimately leading to tissue regeneration. Healing sometimes stalls for various reasons, a key one being…

Read More

How Much Do You Know About Biofilm and Inflammation?

Take our 10-question quiz to find out.

Terms to Know: Biofilm and Inflammation

Biofilm: Colonies of multiphenotype, free-floating bacteria that secrete a polysaccharide matrix that protects the bacteria from immune response and antibiotics.

Chronic wounds: Wounds that stall in the inflammation phase and fail to progress toward healing within 3 months are considered chronic or hard to heal.

Continuous inflammation: When wound healing becomes stalled in the inflammatory phase because of the presence of bacteria and their endotoxins, the wound is unable to move out of the inflammatory phase and into the repair phase.

Back To Top