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Wound Infection Diagnosis and Management: An Overview of Topical Therapies

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Topical antimicrobial and antiseptic treatments have a role in both prevention and management of chronic and infected wounds. The goal of topical agent use in wound infection is to “barricade” or “delay” the growth of pathogenic microorganisms.

This useful guide reviews specific evidence-based practices for the use of topical therapies and the clinical effectiveness of these agents in the treatment of infected wounds. It also provides a list of diagnostic clues to wound infections, as well as a systematic strategy for prevention and management of chronic wounds.

For health care professionals, this guide contains vital information on topical agents used in wound care for patients who are at risk of wound infection or who have infected or chronic wounds.

The guide discusses the following best practices for the use of topical agents, as well as clinical concerns, backed by recent references from the evidence base:

Classic signs of wound infection
Methods of confirming a wound infection diagnosis
Formulations and antibacterial activity of topical antimicrobial and antiseptic agents
Multidrug-resistant organisms, including methicillin-resistant Staphylococcus aureus
Optimizing topical therapy in wound care
Infection prevention strategies for at-risk patients
Definitions of wound contamination, colonization, critical colonization, and infection
Classification of microorganisms
Wound prevention and management sequencing

This guide is generally written to provide practical guidance for all health care professionals in the diagnosis and treatment of infections in their wound patients.

Topical antimicrobial and antiseptic treatments have a role in both prevention and management of chronic and infected wounds. The goal of topical agent use in wound infection is to “barricade” or “delay” the growth of pathogenic microorganisms.

This useful guide reviews specific evidence-based practices for the use of topical antibiotics and the clinical effectiveness of these agents in the treatment of infected wounds. It also provides a list of diagnostic clues to wound infections, as well as a systematic strategy for prevention and management of chronic wounds.

For health care professionals, this guide contains vital information on topical agents used in wound care for patients who are at risk of wound infection or who have infected or chronic wounds.

The guide discusses the following best practices for the use of topical agents, as well as clinical concerns, backed by recent references from the evidence base:

Classic signs of wound infection
Methods of confirming a wound infection diagnosis
Formulations and antibacterial activity of topical antimicrobial and antiseptic agents
Multidrug-resistant organisms, including methicillin-resistant Staphylococcus aureus
Optimizing topical therapy in wound care
Infection prevention strategies for at-risk patients
Definitions of wound contamination, colonization, critical colonization, and infection
Classification of microorganisms
Wound prevention and management sequencing

This guide is generally written to provide practical guidance for all health care professionals in the diagnosis and treatment of infections in their wound patients.

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